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FORUM / MIKES GRIPES /  An interesting technical read on the Virus.

An interesting technical read on the Virus.

Started by Mozart42 REPLIES1,486 VIEWS· 30 Apr 2020, 05:49
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MO
MoonroverPro1,973 posts
01 May 2020, 12:08
#41
01 May 2020, 12:08#41

The good ole aspirin ...the original wonder drug...synthesized one year before the ancient City of Babylon was discovered.

 :-

COVID-19 has a high infection rate and mortality, and serious complications such as heart injury cannot be ignored. Cardiac dysfunction occurred in COVID-19 patients, but the law and mechanism of cardiac dysfunction remains unclear. The occurrence of progressive inflammatory factor storm and coagulation dysfunction in severe and fatal cases of NCP points out a new direction for reducing the incidence of severe and critically ill patients, shortening the length of duration in severe and critically ill patients and reducing the incidence of complications of cardiovascular diseases. Aspirin has the triple effects of inhibiting virus replication, anticoagulant and anti-inflammatory, but it has not received attention in the treatment and prevention of NCP. Although Aspirin is not commonly used in the guidelines for the treatment of NCP, it was widely used in the treatment and prevention of a variety of human diseases after its first synthesis in 1898. Subsequently, aspirin has been confirmed to have antiviral effect on multiple levels. Moreover, one study has confirmed that aspirin can inhibit virus replication by inhibiting prostaglandin E2 (PGE2) in macrophages and upregulation of type I interferon production. Subsequently, pharmacological studies have found that aspirin as an anti-inflammatory and analgesic drug by inhibiting cox-oxidase (COX). Under certain conditions, the platelet is the main contributor of innate immune response, studies have found that in the lung injury model in dynamic neutrophil and platelet aggregation.

In summary, the early use of aspirin in covid-19 patients, which has the effects of inhibiting virus replication, anti-platelet aggregation, anti-inflammatory and anti-lung injury, is expected to reduce the incidence of severe and critical patients, shorten the length of hospital duration and reduce the incidence of cardiovascular complications.


CE
CeradynePro9,374 posts
01 May 2020, 12:34
#42
01 May 2020, 12:34#42

Ou Sharkie, of course we should all go along with your unbiased opinion giving Stav the benefit of the doubt over Moz, all day long. 

And of course all of us have thrown religion into each and every argument on this thread. Oh wait.....

Geez, it would appear that not only do you suffer from TDS, you seem to be having a bad dose of RDS (Religion Derangement Syndrome) as well. 

MO
MozartCaptain49,914 posts
01 May 2020, 16:47
#43
01 May 2020, 16:47#43

The argument with Stav Anger ended when I pointed  out the 1910 to 1940 hockey stick was exactly the same as the 1990 to 2020 hockey stick....but there was no way carbon, which was still very low in 1910 through 1940,  could have been the cause. Solar could though....it spiked during this period.

So no Anger’s googling didn’t win the day. Nor did he win any other point in the debate, because his argument always was....an expert said this. But until the experts can build a model that accurately predicts the climate 10 year in the future, they are just weathermen.


To date every ‘expert’ climate model has hopelessly over predicted temperatures.





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