"Palu [hamstring] and Skelton [pectoral] both suffered injuries in Sunday’s match against Uruguay and scans on Monday confirmed the end of their respective England 2015 campaigns. The news comes days before Australia's crunch match with England on Saturday.
One of the most respected players in recent times for the Wallabies, Palu’s Rugby World Cup ended when he was replaced at half-time against Uruguay, after missing the Wallabies opening match against Fiji though injury.
Skelton was substituted midway through the second half of that match with what was initially believed to be a shoulder injury but scan results on Monday showed he had sustained a pectoral injury.
The 23-year-old will consult a surgeon on his return to Australia.
James Hanson and Sam Carter have been called up to the Wallabies World Cup squad to replace the injured duo.
Hanson and Carter have had an active role with the Wallabies this international season and played in the Test against the USA in Chicago earlier this month.
Hanson has 10 Wallabies caps, having debuted in the 2012 Bledisloe Cup Test at Suncorp Stadium, while Carter has donned the gold jersey 12 times since debuting in 2014.
Both players will join the squad looking for their maiden World Cup appearance.
Wallabies Head Coach Michael Cheika said it was disappointing to see the tournament end for Palu and Skelton after solid contributions by the pair throughout the international season.
"Very few players have the opportunity to play for the Wallabies, let alone at a Rugby World Cup, so from that perspective I’m really gutted for them.
"From a team perspective, they both play important roles in the side and it is disappointing that we need to replace players in our squad."
Cheika said he had complete faith in Hanson and Carter to fill the void left by the duo for the remainder of the tournament.
"Both James and Sam have been part of the team at various stages this season and I am confident they will be able to step up and grasp the opportunity they have been given."
Palu is a great loss - but they have a real star in MacMahon and also have McCalman available.
I think that insofar as Skelton is concerned the ARB may be in trouble - they may face a massive account from Kentucky Fried Chicken and McDonalds Hamburgers for a massive potential loss of income as a result of the injury to Skelton. However, it may save the England food supply from permanent damage. Australia has better locks than this Fatso
